The Seizure Prediction Project
Epilepsy is a severe disease characterized by temporary changes in the bioelectrical functioning of the brain. These changes cause abnormal neuronal synchronization and seizures which affect awareness, movement or sensation. An early in time prediction would considerably increase the quality of life of those patients who cannot be successfully treated by common therapeutic strategies.
Aim of the project
The long-term goal of the project is to develop algorithms that are able to predict epileptic seizures with high sensitivity and specificity. These prediction algorithms could be utilized in a "brain defibrillator", in analogy to cardiac defibrillators. A prediction of seizures at an early stage could trigger an intervention to suppress the upcoming seizure by for instance electrical stimulation. Alternatively, a seizure warning device could be invented that enables behavioral adjustments.
The team
- Prof. Dr. Jens Timmer (Freiburg Center for Data Analysis and Modeling, Freiburg, Germany)
- Prof. Dr. Andreas Schulze-Bonhage (Epilepsy Center, University Medical Center Freiburg, Germany)
- Dr. Bjoern Schelter (Freiburg Center for Data Analysis and Modeling, Freiburg, Germany)
- Dr. Matthias Ihle (Freiburg Center for Data Analysis and Modeling, Freiburg, Germany)
- Hinnerk Feldwisch genannt Drentrup (Freiburg Center for Data Analysis and Modeling, Freiburg, Germany)
- Malenka Killmann (Freiburg Center for Data Analysis and Modeling, Freiburg, Germany)
- Juliane Klatt (Freiburg Center for Data Analysis and Modeling, Freiburg, Germany)
- Armin Brandt (Epilepsy Center, University Medical Center Freiburg, Germany)
Further information
For further information please visit the Seizure prediction project homepage.